Ppcdc Gene Summary [Mouse]

Predicted to enable FMN binding activity; identical protein binding activity; and phosphopantothenoylcysteine decarboxylase activity. Predicted to be involved in coenzyme A biosynthetic process. Predicted to be part of phosphopantothenoylcysteine decarboxylase complex. Is expressed in several structures, including alimentary system; brain; respiratory system; sensory organ; and urinary system. Orthologous to human PPCDC (phosphopantothenoylcysteine decarboxylase). [provided by Alliance of Genome Resources, Jul 2025]

Details

Type
Protein Coding
Official Symbol
Ppcdc
Official Name
phosphopantothenoylcysteine decarboxylase [Source:MGI Symbol;Acc:MGI:1914062]
Ensembl ID
ENSMUSG00000063849
Bio databases IDs NCBI: 66812 Ensembl: ENSMUSG00000063849
Aliases phosphopantothenoylcysteine decarboxylase
Synonyms 1810057I13RIK, 8430432M10RIK, coaC, MDS018, NEWGENE 1306267, phosphopantothenoylcysteine decarboxylase, RGD1306267
Species
Mouse, Mus musculus
OrthologiesHumanRat

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Ppcdc often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • phosphopantothenoylcysteine decarboxylase
  • flavoprotein
  • phosphopantothenoylcysteine decarboxylase, streptococcal
  • FMN binding
  • enzyme
  • protein binding
  • identical protein binding

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
  • systemic lupus erythematosus
  • eczema
  • amenorrhea
regulated by
regulates
  • coenzyme A
role in cell
  • survival
  • morphology

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Cytoplasm
  • cytosol

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the mouse Ppcdc gene, providing context for its role in the cell.

Biological Process

Functions and activities the gene product is involved in
  • coenzyme A biosynthetic process

Cellular Component

Where in the cell the gene product is active
  • cytosol
  • phosphopantothenoylcysteine decarboxylase complex

Molecular Function

What the gene product does at the molecular level
  • phosphopantothenoylcysteine decarboxylase activity
  • identical protein binding
  • protein binding
  • FMN binding

Gene-Specific Assays for Results You Can Trust

Streamline your workflow with assays designed for this gene. Our targeted dPCR and qPCR assays help you generate meaningful data – efficiently and accurately.