Mei1 Gene Summary [Mouse]
Acts upstream of or within germ cell development; meiotic nuclear division; and meiotic spindle organization. Is expressed in brain; ovary; and testis. Human ortholog(s) of this gene implicated in gestational trophoblastic neoplasm. Orthologous to human MEI1 (meiotic double-stranded break formation protein 1). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Mei1 |
| Official Name | meiotic double-stranded break formation protein 1 [Source:MGI Symbol;Acc:MGI:3028590] |
| Ensembl ID | ENSMUSG00000068117 |
| Bio databases IDs | |
| Aliases | meiotic double-stranded break formation protein 1 |
| Synonyms | 4932408F18Rik, HYDM3, LOC200321, meiotic double-stranded break formation protein 1, SPATA38 |
| Species | Mouse, Mus musculus |
| Orthologies |
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
- recurrent hydatidiform mole type 3
- refractive error
- atrial fibrillation
- major depression
- anaplastic thyroid carcinoma
- anaplastic thyroid cancer
- epithelial thyroid cancer
- sarcoidosis
role in cell
- development
- organization
- generation
- meiosis I
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Unknown
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Mei1 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- meiosis I