Mfap1a Gene Summary [Mouse]
Predicted to be an extracellular matrix structural constituent. Predicted to be involved in mRNA splicing, via spliceosome. Located in collagen-containing extracellular matrix. Orthologous to human MFAP1 (microfibril associated protein 1). [provided by Alliance of Genome Resources, Apr 2025]
Details
| Type | Protein Coding |
| Official Symbol | Mfap1a |
| Official Name | microfibrillar-associated protein 1A [Source:MGI Symbol;Acc:MGI:1914782] |
| Ensembl ID | ENSMUSG00000068479 |
| Bio databases IDs | |
| Aliases | microfibrillar-associated protein 1A |
| Synonyms | 4432409M24Rik, AMP, Mfap1a, Mfap1b, microfibril associated protein 1, microfibrillar-associated protein 1A, RGD1562232 |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Mfap1a often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- Microfibril-associated/Pre-mRNA processing
- protein binding
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Nucleus
- interchromatin granule cluster fractions
- centrosome
- spliceosomes
- nucleoplasm
- microfibrils
- extracellular matrix
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Mfap1a gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- nuclear mRNA splicing, via spliceosome
Cellular Component
Where in the cell the gene product is active
- nucleus
- centrosome
- microfibril
- U2-type spliceosomal complex
- U2-type precatalytic spliceosome
- nucleoplasm
Molecular Function
What the gene product does at the molecular level
- protein binding
- RNA binding