Scn2b

Enables voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization and voltage-gated sodium channel activity involved in cardiac muscle cell action potential. Acts upstream of or within with a positive effect on cardiac conduction and gene expression. Acts upstream of or within response to heat and sodium ion transport. Is active in T-tubule. Is expressed in several structures, including cranial ganglion and dorsal root ganglion. Human ortholog(s) of this gene implicated in familial atrial fibrillation. Orthologous to human SCN2B (sodium voltage-gated channel beta subunit 2). [provided by Alliance of Genome Resources, Jul 2025]

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Scn2b often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.

Biological processes and signaling networks where the Scn2b gene in mouse plays a role, providing insight into its function and relevance in health or disease.

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.

Describes the biological processes, cellular components, and molecular functions associated with the mouse Scn2b gene, providing context for its role in the cell.