Wdr90 Gene Summary [Mouse]

Predicted to enable microtubule binding activity. Predicted to be involved in centriole elongation and cilium assembly. Predicted to be located in centriolar satellite. Predicted to be active in centriole. Is expressed in choroid invagination; diencephalon roof plate; metencephalon part of 4th ventricle choroid plexus; and olfactory epithelium. Orthologous to human WDR90 (WD repeat domain 90). [provided by Alliance of Genome Resources, Apr 2025]

Details

Type
Retained Intron
Official Symbol
Wdr90
Official Name
WD repeat domain 90 [Source:MGI Symbol;Acc:MGI:1921267]
Ensembl ID
ENSMUSG00000073434
Bio databases IDs NCBI: 106618 Ensembl: ENSMUSG00000073434
Aliases WD repeat domain 90
Synonyms 3230401M21Rik, C16ORF15, C16ORF16, C16ORF17, C16orf18, C16ORF19, FLJ36290, KIAA1924, LOC102555298, LOC197336, mKIAA1924, POC16, RGD1561785, WD repeat domain 90
Species
Mouse, Mus musculus
OrthologiesHumanRat

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Wdr90 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • microtubule binding
  • WD40 repeats
  • WD domain, G-beta repeat
  • CFA20 domain
  • WD40
  • protein binding

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
  • insomnia
regulated by
role in cell
  • assembly
  • elongation

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Cytoplasm
  • Plasma Membrane
  • basal bodies
  • centrosome
  • centriole

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the mouse Wdr90 gene, providing context for its role in the cell.

Biological Process

Functions and activities the gene product is involved in
  • cilium morphogenesis

Cellular Component

Where in the cell the gene product is active
  • centrosome
  • cytoplasm
  • centriole

Molecular Function

What the gene product does at the molecular level
  • protein binding

Gene-Specific Assays for Results You Can Trust

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