Il4i1 Gene Summary [Mouse]

This locus represents naturally-occurring readthrough transcription between Nup62 (nucleoporin 62) and Il4i1 (interleukin 4 induced 1). It encodes a protein sharing similarity with the protein encoded by Il4i1, but with a longer and distinct N-terminus. [provided by RefSeq, Aug 2015]

Details

Type
Processed Transcript
Official Symbol
Il4i1
Official Name
interleukin 4 induced 1 [Source:MGI Symbol;Acc:MGI:109552]
Ensembl ID
ENSMUSG00000074141
Bio databases IDs NCBI: 14204 NCBI: 100328588 Ensembl: ENSMUSG00000074141
Aliases interleukin 4 induced 1
Synonyms Fig1, Fig1-ps, Gm21948, H-4, H46, Il4i1, Il4i1b, interleukin 4 induced 1, interleukin 4 induced 1B, LAAO, LAO, mFIG1, mIL4I1, Nup62-il4i1
Species
Mouse, Mus musculus

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Il4i1 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • L-amino-acid oxidase
  • enzyme
  • Flavin containing amine oxidoreductase

Pathways

Biological processes and signaling networks where the Il4i1 gene in mouse plays a role, providing insight into its function and relevance in health or disease.

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
regulates
  • Ca2+
  • RPS6
  • PTPN6
  • IgG1
  • AKT
  • IgG2b
  • IgG
  • p70 S6k
  • IgM
regulated by
  • CALCA
  • STAT6
  • lipid A
  • Lmp2a
  • TNF
  • TP53
  • calcitriol
  • Mycobacterium tuberculosis H37Rv
  • PTGER4
  • L-triiodothyronine
phenotypes
  • abnormal QT variability
  • decreased circulating potassium level
  • decreased circulating unsaturated transferrin level
  • increased circulating iron level
  • preweaning lethality incomplete penetrance
  • abnormal cued conditioning behavior
role in cell
  • phosphorylation in
  • proliferation
  • mobilization in
  • accumulation
  • differentiation

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Cytoplasm
  • Extracellular Space
  • lysosome
  • immunological synapses
  • sperm midpiece
  • acrosome

Gene-Specific Assays for Results You Can Trust

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