Ifit3 Gene Summary [Mouse]

Predicted to enable identical protein binding activity. Involved in response to stilbenoid. Acts upstream of or within cellular response to interferon-beta and response to bacterium. Predicted to be located in mitochondrion. Predicted to be active in cytosol. Is expressed in alimentary system; eye; face; liver; and nervous system. Orthologous to human IFIT3 (interferon induced protein with tetratricopeptide repeats 3). [provided by Alliance of Genome Resources, Jul 2025]

Details

Type
Protein Coding
Official Symbol
Ifit3
Official Name
interferon-induced protein with tetratricopeptide repeats 3 [Source:MGI Symbol;Acc:MGI:1101055]
Ensembl ID
ENSMUSG00000074896
Bio databases IDs NCBI: 15959 Ensembl: ENSMUSG00000074896
Aliases interferon-induced protein with tetratricopeptide repeats 3
Synonyms Garg49, I830012O16Rik, Ifi49, Ifit3, Ifit3b, interferon-induced protein with tetratricopeptide repeats 3, interferon-induced protein with tetratricopeptide repeats 3B, P49
Species
Mouse, Mus musculus

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Ifit3 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • protein binding
  • identical protein binding
  • tetratricopeptide repeat

Pathways

Biological processes and signaling networks where the Ifit3 gene in mouse plays a role, providing insight into its function and relevance in health or disease.

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
  • insulin-dependent diabetes mellitus
  • Huntington disease
regulated by

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Cytoplasm
  • Mitochondria
  • cytosol

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