Zfp541 Gene Summary [Mouse]
Predicted to enable transcription corepressor activity. Involved in male meiotic nuclear division; negative regulation of DNA-templated transcription; and positive regulation of DNA-templated transcription. Located in nucleus. Part of histone deacetylase complex. Is expressed in testis. Orthologous to human ZNF541 (zinc finger protein 541). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Zfp541 |
| Official Name | zinc finger protein 541 [Source:MGI Symbol;Acc:MGI:3647699] |
| Ensembl ID | ENSMUSG00000078796 |
| Bio databases IDs | |
| Aliases | zinc finger protein 541 |
| Synonyms | EG666528, Zfp541, zinc finger protein 541 |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Zfp541 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- Zinc finger, C2H2 type
- SANT
- zinc finger
- transcription regulator
- SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains
- ELM2 domain
- Myb-like DNA-binding domain
- protein binding
- C2H2-type zinc finger
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Nucleus
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Zfp541 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- negative regulation of transcription, DNA-dependent
- positive regulation of transcription, DNA-dependent
- spermatogenesis
- male meiosis
- cell differentiation
- regulation of transcription, DNA-dependent
- regulation of transcription from RNA polymerase II promoter
Cellular Component
Where in the cell the gene product is active
- transcription factor complex
- nucleus
- histone deacetylase complex
Molecular Function
What the gene product does at the molecular level
- protein binding
- metal ion binding
- transcription corepressor activity