Tmem182 Gene Summary [Mouse]
Involved in myotube cell development involved in skeletal muscle regeneration; negative regulation of myoblast differentiation; and negative regulation of myoblast fusion. Predicted to be located in plasma membrane. Orthologous to human TMEM182 (transmembrane protein 182). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Tmem182 |
| Official Name | transmembrane protein 182 [Source:MGI Symbol;Acc:MGI:1923725] |
| Ensembl ID | ENSMUSG00000079588 |
| Bio databases IDs | |
| Aliases | transmembrane protein 182 |
| Synonyms | 2310079P10Rik, RGD1563696, transmembrane protein 182 |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Tmem182 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- PMP-22/EMP/MP20/Claudin family
- protein binding
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Unknown
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Tmem182 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- muscle organ development
- myotube differentiation involved in skeletal muscle regeneration
- myotube cell development involved in skeletal muscle regeneration
- negative regulation of myoblast differentiation
Cellular Component
Where in the cell the gene product is active
- plasma membrane
Molecular Function
What the gene product does at the molecular level
- protein binding