Ccdc85c Gene Summary [Mouse]
Involved in cerebral cortex development. Acts upstream of or within several processes, including Notch signaling pathway; establishment of cell polarity; and radial glial cell differentiation. Located in apical junction complex. Is expressed in brain; brain pia mater; brain subventricular zone; diencephalon; and telencephalon. Used to study hydrocephalus. Orthologous to human CCDC85C (coiled-coil domain containing 85C). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Ccdc85c |
| Official Name | coiled-coil domain containing 85C [Source:MGI Symbol;Acc:MGI:3644008] |
| Ensembl ID | ENSMUSG00000084883 |
| Bio databases IDs | |
| Aliases | coiled-coil domain containing 85C |
| Synonyms | C14orf136, coiled-coil domain containing 85C, EG668158, Gm265, Gm9010, hhy, LOC100128667, LOC684166 |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Ccdc85c often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- protein binding
- CCDC85 family
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Plasma Membrane
- cell junction
- intercellular junctions
- nuclear speckles
- cell-cell adherens junctions
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Ccdc85c gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- cerebral cortex development
Cellular Component
Where in the cell the gene product is active
- adherens junction
- tight junction
- apical junction complex
Molecular Function
What the gene product does at the molecular level
- protein binding