Hoxa11os Gene Summary [Mouse]
This gene produces a long non-coding RNA in antisense to transcription of the homeobox A11 gene. This transcript may associate with chromatin factors such as Polycomb repressive complex and act as a sponge for microRNAs, thereby participating in the regulation of expression of target genes. High levels of this transcript may be associated with tumor progression. [provided by RefSeq, Dec 2017]
Details
| Type | Long Non-Coding RNA |
| Official Symbol | Hoxa11os |
| Official Name | homeobox A11, opposite strand [Source:MGI Symbol;Acc:MGI:107208] |
| Ensembl ID | ENSMUSG00000086427 |
| Bio databases IDs | |
| Aliases | homeobox A11, opposite strand |
| Synonyms | AABR07060585.2, AABR07073021.1, homeobox A11, opposite strand, HOXA11 antisense RNA, HOXA11-AS1, Hoxa11os, HOXA11S, HOXA-AS5, LncHOXA11, LOC100909487, LOC100911785, NCRNA00076, RGD1564419 |
| Species | Mouse, Mus musculus |
| Orthologies |
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
- arteriosclerosis
- metastasis
- organismal death
- neurological disorder
- non-small cell lung cancer
- hypopharyngeal squamous cell carcinoma
- squamous cell cancer of the hypopharynx
regulated by
- LDL
- VEGF
- fibroblasts
- SBDS
- Cohesin
role in cell
- production in
- invasion by
- apoptosis
- phosphorylation in
- molecular cleavage in
- expression in
- quantity
- activation
- proliferation
- binding in
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Nucleus
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Hoxa11os gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- negative regulation of gene expression