HOXA11-AS Gene Summary [Human]
This gene produces a long non-coding RNA in antisense to transcription of the homeobox A11 gene. This transcript may associate with chromatin factors such as Polycomb repressive complex and act as a sponge for microRNAs, thereby participating in the regulation of expression of target genes. High levels of this transcript may be associated with tumor progression. [provided by RefSeq, Dec 2017]
Details
| Type | Long Non-Coding RNA |
| Official Symbol | HOXA11-AS |
| Official Name | HOXA11 antisense RNA [Source:HGNC Symbol;Acc:HGNC:24957] |
| Ensembl ID | ENSG00000240990 |
| Bio databases IDs | |
| Aliases | HOXA11 antisense RNA, non-protein coding RNA 76, HOXA cluster antisense RNA 5 (non-protein coding), HOXA11 antisense RNA 1 (non-protein coding) |
| Synonyms | AABR07060585.2, AABR07073021.1, homeobox A11, opposite strand, HOXA11 antisense RNA, HOXA11-AS1, Hoxa11os, HOXA11S, HOXA-AS5, LncHOXA11, LOC100909487, LOC100911785, NCRNA00076, RGD1564419 |
| Species | Human, Homo sapiens |
| Orthologies |
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
- arteriosclerosis
- metastasis
- organismal death
- neurological disorder
- non-small cell lung cancer
- hypopharyngeal squamous cell carcinoma
- squamous cell cancer of the hypopharynx
role in cell
- production in
- invasion by
- apoptosis
- phosphorylation in
- molecular cleavage in
- expression in
- quantity
- activation
- proliferation
- binding in
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Nucleus
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the human HOXA11-AS gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- negative regulation of gene expression