Eif4ebp3 Gene Summary [Mouse]
Predicted to enable eukaryotic initiation factor 4E binding activity. Predicted to be involved in negative regulation of translational initiation. Predicted to be located in nucleus. Predicted to be active in cytoplasm. Is expressed in gut; male reproductive gland or organ; and metanephros. Orthologous to human EIF4EBP3 (eukaryotic translation initiation factor 4E binding protein 3). [provided by Alliance of Genome Resources, Apr 2025]
Details
| Type | Protein Coding |
| Official Symbol | Eif4ebp3 |
| Official Name | eukaryotic translation initiation factor 4E binding protein 3 [Source:MGI Symbol;Acc:MGI:1270847] |
| Ensembl ID | ENSMUSG00000090264 |
| Bio databases IDs | |
| Aliases | eukaryotic translation initiation factor 4E binding protein 3 |
| Synonyms | 4E-BP3, eukaryotic translation initiation factor 4E binding protein 3 |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Eif4ebp3 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- Eukaryotic translation initiation factor 4E binding protein (EIF4EBP)
- protein binding
- eIF4E binding domain
Pathways
Biological processes and signaling networks where the Eif4ebp3 gene in mouse plays a role, providing insight into its function and relevance in health or disease.
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Eif4ebp3 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- negative regulation of translational initiation
Cellular Component
Where in the cell the gene product is active
- nucleus
- eukaryotic translation initiation factor 4F complex
- cytoplasm
- membrane
Molecular Function
What the gene product does at the molecular level
- protein binding
- translation repressor activity
- eukaryotic initiation factor 4E binding