H4c14 Gene Summary [Mouse]
Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. This structure consists of approximately 146 bp of DNA wrapped around a nucleosome, an octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene is intronless and encodes a replication-dependent histone that is a member of the histone H4 family. [provided by RefSeq, Aug 2015]
Details
| Type | Protein Coding |
| Official Symbol | H4c14 |
| Official Name | H4 clustered histone 14 [Source:MGI Symbol;Acc:MGI:2140113] |
| Ensembl ID | ENSMUSG00000091405 |
| Bio databases IDs | |
| Aliases | H4 clustered histone 14 |
| Synonyms | H4, H4c1, H4c11, H4c12, H4c16, H4c2, H4c3, H4c4, H4c6, H4c8, H4c9, H4 clustered histone 14, H4 clustered histone 3, H4f16, Hist2h4 |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse H4c14 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- histone fold domain (HFD) superfamily
- TATA box binding protein associated factor (TAF)
- protein binding
- TATA box binding protein associated factor
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Nucleus
- nucleosomes