Prps1l1 Gene Summary [Mouse]
Predicted to enable ribose phosphate diphosphokinase activity. Predicted to be involved in 5-phosphoribose 1-diphosphate biosynthetic process and purine nucleotide biosynthetic process. Predicted to be part of ribose phosphate diphosphokinase complex. Predicted to be active in cytoplasm. Is expressed in cerebral cortex; heart; and liver. Orthologous to human PRPS1L1 (phosphoribosyl pyrophosphate synthetase 1 like 1). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Prps1l1 |
| Official Name | phosphoribosyl pyrophosphate synthetase 1-like 1 [Source:MGI Symbol;Acc:MGI:1922706] |
| Ensembl ID | ENSMUSG00000092305 |
| Bio databases IDs | |
| Aliases | phosphoribosyl pyrophosphate synthetase 1-like 1 |
| Synonyms | 1700011K15RIK, phosphoribosyl pyrophosphate synthetase 1-like 1, PRPS1, PRPS3, PRPSL, PRS-III |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Prps1l1 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- kinase
- ATP binding
- ribose-phosphate diphosphokinase
- protein homodimerization
- ribose-phosphate pyrophosphokinase
- Phosphoribosyl transferase (PRT)-type I domain
- Phosphoribosyl synthetase-associated domain
- N-terminal domain of ribose phosphate pyrophosphokinase
- PRK00934
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- cytoplasmic droplets
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Prps1l1 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- ribonucleoside monophosphate biosynthetic process
- male gonad development
- purine nucleotide biosynthetic process
- 5-phosphoribose 1-diphosphate biosynthetic process
Cellular Component
Where in the cell the gene product is active
- cytoplasm
- ribose phosphate diphosphokinase complex
Molecular Function
What the gene product does at the molecular level
- magnesium ion binding
- ATP binding
- protein homodimerization activity
- ribose phosphate diphosphokinase activity
- kinase activity