Cmtm4 Gene Summary [Mouse]
Predicted to be active in membrane. Is expressed in gut; nose; submandibular gland primordium; and urinary system. Orthologous to human CMTM4 (CKLF like MARVEL transmembrane domain containing 4). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Cmtm4 |
| Official Name | CKLF-like MARVEL transmembrane domain containing 4 [Source:MGI Symbol;Acc:MGI:2142888] |
| Ensembl ID | ENSMUSG00000096188 |
| Bio databases IDs | |
| Aliases | CKLF-like MARVEL transmembrane domain containing 4 |
| Synonyms | CKLF-like MARVEL transmembrane domain containing 4, CKLFSF4, Gm9853, LOC681504, RGD1565098 |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Cmtm4 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- Membrane-associating domain
- protein binding
- cytokine
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
- neoplasia
- epithelial cancer
- epithelial neoplasia
- esophageal carcinoma
- esophageal carcinoma formation
- imiquimod-induced psoriasis
- rectal adenocarcinoma
- colorectal carcinomagenesis
- rectum cancer
- prostatic adenocarcinoma
role in cell
- expression in
- production in
- phosphorylation in
- activation in
- recruitment in
- number
- function
- recruitment
- glycosylation in
- gefitinib sensitivity
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Extracellular Space
- cellular membrane
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Cmtm4 gene, providing context for its role in the cell.
Cellular Component
Where in the cell the gene product is active
- membrane
Molecular Function
What the gene product does at the molecular level
- protein binding