Mrgpra2b Gene Summary [Mouse]

Predicted to enable G protein-coupled receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway. Predicted to be active in plasma membrane. Orthologous to human MRGPRX3 (MAS related GPR family member X3) and MRGPRX4 (MAS related GPR family member X4). [provided by Alliance of Genome Resources, Apr 2025]

Details

Type
Protein Coding
Official Symbol
Mrgpra2b
Official Name
MAS-related GPR, member A2B [Source:MGI Symbol;Acc:MGI:3033098]
Ensembl ID
ENSMUSG00000096719
Bio databases IDs NCBI: 235712 Ensembl: ENSMUSG00000096719
Aliases MAS-related GPR, member A2B
Synonyms EG668725, mAde2R, MAS related GPR family member X3, MAS-related GPR, member A1, MAS-related GPR, member A2A, MAS-related GPR, member A2B, MAS-related GPR, member A9, Mgrg1, MrgA, MrgA1, Mrga10, MrgA2, MrgA9, Mrgpra, Mrgpra1, Mrgpra2, Mrgpra2b, Mrgpra9, Mrgprx3
Species
Mouse, Mus musculus
OrthologiesRat

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Mrgpra2b often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • G-protein coupled receptor
  • GTP binding
  • binding protein
  • neuropeptide receptor
  • 7 transmembrane receptor (rhodopsin family)
  • seven-transmembrane G protein-coupled receptor superfamily

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
  • depressive disorder
regulated by
role in cell
  • migration

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Plasma Membrane
  • cellular membrane

Gene-Specific Assays for Results You Can Trust

Streamline your workflow with assays designed for this gene. Our targeted dPCR and qPCR assays help you generate meaningful data – efficiently and accurately.