Rpl24 Gene Summary [Mouse]
A structural constituent of ribosome. Acts upstream of or within several processes, including exit from mitosis; nervous system development; and ribosomal large subunit assembly. Located in cytoplasm. Part of cytosolic large ribosomal subunit. Is active in synapse. Is expressed in embryo; metanephros; spleen; and thymus. Used to study optic atrophy. Orthologous to human RPL24 (ribosomal protein L24). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Rpl24 |
| Official Name | ribosomal protein L24 [Source:MGI Symbol;Acc:MGI:1915443] |
| Ensembl ID | ENSMUSG00000098274 |
| Bio databases IDs | |
| Aliases | ribosomal protein L24 |
| Synonyms | 0610008L05Rik, BST, eL24, HEL-S-310, L24, Ribosomal protein L24, Zbtb11 |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Rpl24 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- structural constituent of ribosome
- Ribosomal protein L24e
- protein binding
- Putative metal-binding domain of cation transport ATPase
- RNA binding
- Ribosomal_L24e_L24
Pathways
Biological processes and signaling networks where the Rpl24 gene in mouse plays a role, providing insight into its function and relevance in health or disease.
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
- COVID-19
regulates
- TP53
- Ribosomal Subunit 60s
- EEF2
role in cell
- expression in
- proliferation
- cell viability
- survival
- checkpoint control
- guidance
- translation in
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- interchromatin granule cluster fractions
- ribosome
- Nucleus
- Endoplasmic Reticulum
- cytosol
- nucleoli
- synapse
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Rpl24 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- retinal ganglion cell axon guidance
- retina development in camera-type eye
- cytoplasmic translation
- exit from mitosis
- optic nerve development
- translation
Cellular Component
Where in the cell the gene product is active
- extracellular vesicular exosome
- cytosolic ribosome
- cytoplasm
- membrane
- cytosol
- endoplasmic reticulum
- synapse
- cytosolic large ribosomal subunit
Molecular Function
What the gene product does at the molecular level
- RNA binding
- protein binding
- structural constituent of ribosome
- cadherin binding
- mRNA binding