Bcl2a1d Gene Summary [Mouse]
Enables cysteine-type endopeptidase inhibitor activity involved in apoptotic process. Acts upstream of or within T cell differentiation and T cell receptor signaling pathway. Predicted to be located in cytoplasm. Predicted to be active in mitochondrial outer membrane. Is expressed in several structures, including adipose tissue; craniocervical region bone; hemolymphoid system; liver; and respiratory system. Orthologous to human BCL2A1 (BCL2 related protein A1). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Bcl2a1d |
| Official Name | B cell leukemia/lymphoma 2 related protein A1d [Source:MGI Symbol;Acc:MGI:1278325] |
| Ensembl ID | ENSMUSG00000099974 |
| Bio databases IDs | |
| Aliases | B cell leukemia/lymphoma 2 related protein A1d |
| Synonyms | A1, A1-b, A1-d, B cell leukaemia/lymphoma 2 related protein A1a, B cell leukaemia/lymphoma 2 related protein A1b, B cell leukaemia/lymphoma 2 related protein A1d, B cell leukemia/lymphoma 2 related protein A1a, B cell leukemia/lymphoma 2 related protein A1b, B cell leukemia/lymphoma 2 related protein A1d, Bcl2a1, Bcl2a1b, Bcl2a1d, Bfl-1, Bfl-1/A1, Hbpa1, U23778, U23781 |
| Species | Mouse, Mus musculus |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Bcl2a1d often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- Bcl-2_like
- binding protein
- caspase inhibitor activity
- protein domain specific binding
- protein binding
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
- infection by parasite
role in cell
- cell death
- apoptosis
- quantity
- necrosis
- proliferation
- differentiation
- survival
- number
- function
- lifespan
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- perinuclear region