Ahnak2 Gene Summary [Mouse]

Predicted to be involved in regulation of RNA splicing. Predicted to be located in cytosol and plasma membrane. Predicted to be active in cytoplasm and nucleus. Is expressed in dorsal root ganglion and trigeminal ganglion. Orthologous to human AHNAK2 (AHNAK nucleoprotein 2). [provided by Alliance of Genome Resources, Jul 2025]

Details

Type
Protein Coding
Official Symbol
Ahnak2
Official Name
AHNAK nucleoprotein 2 [Source:NCBI gene (formerly Entrezgene);Acc:100041194]
Ensembl ID
ENSMUSG00000118667
Bio databases IDs NCBI: 100041194 Ensembl: ENSMUSG00000118667
Aliases AHNAK nucleoprotein 2
Synonyms AHNAK nucleoprotein 2, C14orf78, Gm1185, Gm72, KIAA2019, LOC100047183, LOC100503606, LOC283639, LOC730269, RGD1309696
Species
Mouse, Mus musculus
OrthologiesHuman

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Ahnak2 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • Domain present in PSD-95, Dlg, and ZO-1/2
  • canonical PDZ domain
  • protein binding

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
  • systemic sclerosis
  • systemic lupus erythematosus
  • COVID-19
  • diabetic nephropathy
  • thyroid carcinoma
  • epithelial thyroid cancer
regulated by

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Cytoplasm
  • Plasma Membrane
  • cytosol

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the mouse Ahnak2 gene, providing context for its role in the cell.

Biological Process

Functions and activities the gene product is involved in
  • regulation of RNA splicing

Cellular Component

Where in the cell the gene product is active
  • T-tubule
  • nucleus
  • cytoplasm
  • sarcolemma
  • cytosol
  • costamere
  • plasma membrane

Molecular Function

What the gene product does at the molecular level
  • protein binding

Gene-Specific Assays for Results You Can Trust

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