Tmed5 Gene Summary [Rat]

Involved in Golgi ribbon formation. Located in cis-Golgi network; endoplasmic reticulum exit site; and endoplasmic reticulum-Golgi intermediate compartment. [provided by Alliance of Genome Resources, Apr 2022]

Details

Type
Protein Coding
Official Symbol
Tmed5
Official Name
transmembrane p24 trafficking protein 5 [Source:RGD Symbol;Acc:1359437]
Ensembl ID
ENSRNOG00000000073
Bio databases IDs NCBI: 289883 Ensembl: ENSRNOG00000000073
Aliases transmembrane p24 trafficking protein 5
Synonyms 3110020O18Rik, 4432412D15Rik, CGI-100, LRRG00120, p24g2, p24gamma2, p28, transmembrane p24 trafficking protein 5
Species
Rat, Rattus norvegicus
OrthologiesHumanMouse

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Tmed5 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • protein binding
  • emp24/gp25L/p24 family/GOLD

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
  • cleft lip
  • preeclampsia
regulated by
role in cell
  • formation

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Cytoplasm
  • pH resistant lipid raft fraction
  • Endoplasmic Reticulum
  • ER-to-Golgi intermediate compartment
  • endoplasmic reticulum membrane
  • cis Golgi networks

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the rat Tmed5 gene, providing context for its role in the cell.

Biological Process

Functions and activities the gene product is involved in
  • ER to Golgi vesicle-mediated transport
  • intracellular protein transport
  • Golgi ribbon formation

Cellular Component

Where in the cell the gene product is active
  • endoplasmic reticulum membrane
  • cis-Golgi network
  • endoplasmic reticulum exit site
  • ER to Golgi transport vesicle
  • Golgi apparatus
  • endoplasmic reticulum
  • endoplasmic reticulum-Golgi intermediate compartment
  • endoplasmic reticulum-Golgi intermediate compartment membrane

Molecular Function

What the gene product does at the molecular level
  • protein binding
  • cargo receptor activity

Gene-Specific Assays for Results You Can Trust

Streamline your workflow with assays designed for this gene. Our targeted dPCR and qPCR assays help you generate meaningful data – efficiently and accurately.