Cd164 Gene Summary [Rat]
Predicted to be involved in muscle organ development. Predicted to act upstream of or within heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules. Located in endosome. Human ortholog(s) of this gene implicated in autosomal dominant nonsyndromic deafness 66. Orthologous to human CD164 (CD164 molecule). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Cd164 |
| Official Name | CD164 molecule [Source:RGD Symbol;Acc:70942] |
| Ensembl ID | ENSRNOG00000000304 |
| Bio databases IDs | |
| Aliases | CD164 molecule |
| Synonyms | A115, A24, CD164 antigen, CD164 molecule, DFNA66, Endolyn, MGC, MGC-24, MGC-24v, MSSP, MUC-24 |
| Species | Rat, Rattus norvegicus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Cd164 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- Multi-glycosylated core protein 24 (MGC-24), sialomucin
- extracellular domain
- protein binding
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
- chronic obstructive pulmonary disease
- Alzheimer disease
- severe acute respiratory syndrome
- androgenic alopecia
- lung carcinoma process
- clonal hematopoiesis
- autosomal dominant deafness type 66
- nonsyndromic autosomal dominant hearing impairment
- lung carcinoma
- infection by HIV-1
role in cell
- proliferation
- differentiation
- growth
- apoptosis
- adhesion
- viral entry in
- cell-cell adhesion
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Plasma Membrane
- cell surface
- Extracellular Space
- endosomes
- lysosome
- early endosomes
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the rat Cd164 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- muscle organ development
- immune response
- signal transduction
- hemopoiesis
- negative regulation of cell adhesion
- heterophilic cell-cell adhesion
- cell adhesion
Cellular Component
Where in the cell the gene product is active
- endosome
- endosome membrane
- extracellular region
- plasma membrane
- lysosomal membrane
- lysosome
Molecular Function
What the gene product does at the molecular level
- protein binding