Ndufv3 Gene Summary [Rat]
Predicted to be involved in mitochondrial ATP synthesis coupled electron transport. Predicted to be located in mitochondrion. Predicted to be part of respiratory chain complex I. Predicted to be active in mitochondrial inner membrane. Orthologous to human NDUFV3 (NADH:ubiquinone oxidoreductase subunit V3). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Ndufv3 |
| Official Name | NADH:ubiquinone oxidoreductase subunit V3 [Source:RGD Symbol;Acc:621020] |
| Ensembl ID | ENSRNOG00000001182 |
| Bio databases IDs | |
| Aliases | NADH:ubiquinone oxidoreductase subunit V3 |
| Synonyms | 1500032D16RIK, CI-10k, CI-9KD, Mipp65, MITOCHONDRIAL COMPLEX 1-10KDA subunit, NADH:ubiquinone oxidoreductase core subunit V3, NADH:ubiquinone oxidoreductase subunit V3, Ndufv3l |
| Species | Rat, Rattus norvegicus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Ndufv3 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- NADH dehydrogenase [ubiquinone] flavoprotein 3, mitochondrial
- enzyme
- protein binding
- NADH2 dehydrogenase (ubiquinone)
Pathways
Biological processes and signaling networks where the Ndufv3 gene in rat plays a role, providing insight into its function and relevance in health or disease.
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
- obesity
- early onset hypertension
- chromophobe renal cell carcinoma
- chromophobe renal cancer
- adult acute myeloid leukemia
- Huntington disease
- insulin resistance
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- Mitochondria
- mitochondrial inner membrane
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the rat Ndufv3 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- transmembrane transport
- mitochondrial electron transport, NADH to ubiquinone
- aerobic respiration
- mitochondrial ATP synthesis coupled electron transport
- mitochondrial ATP synthesis coupled proton transport
Cellular Component
Where in the cell the gene product is active
- respiratory chain complex I
- mitochondrion
- mitochondrial inner membrane
Molecular Function
What the gene product does at the molecular level
- protein binding
- RNA binding
- NADH dehydrogenase (ubiquinone) activity