Anapc7 Gene Summary [Rat]
Predicted to enable enzyme-substrate adaptor activity and protein phosphatase binding activity. Predicted to be involved in several processes, including anaphase-promoting complex-dependent catabolic process; positive regulation of mitotic metaphase/anaphase transition; and protein polyubiquitination. Predicted to be located in several cellular components, including heterochromatin; intercellular bridge; and mitotic spindle. Predicted to be part of anaphase-promoting complex. Orthologous to human ANAPC7 (anaphase promoting complex subunit 7). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Anapc7 |
| Official Name | anaphase promoting complex subunit 7 [Source:RGD Symbol;Acc:1311927] |
| Ensembl ID | ENSRNOG00000001283 |
| Bio databases IDs | |
| Aliases | anaphase promoting complex subunit 7 |
| Synonyms | anaphase promoting complex subunit 7, APC7, FERBON |
| Species | Rat, Rattus norvegicus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Anapc7 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- protein phosphatase binding
- protein binding activity, bridging
- Tetratricopeptide repeats
- tetratricopeptide repeat
Pathways
Biological processes and signaling networks where the Anapc7 gene in rat plays a role, providing insight into its function and relevance in health or disease.
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Nucleus
- microtubule cytoskeleton
- heterochromatin
- intracellular membrane-bounded organelle
- spindle apparatus
- cytoplasmic bridges
- cytosol
- nucleoplasm
- mitotic spindle
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the rat Anapc7 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- cell division
- regulation of meiotic cell cycle
- protein K11-linked ubiquitination
- protein K48-linked ubiquitination
- anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process
- positive regulation of mitotic metaphase/anaphase transition
- brain development
- regulation of mitotic cell cycle
- protein ubiquitination
Cellular Component
Where in the cell the gene product is active
- nucleus
- heterochromatin
- microtubule cytoskeleton
- anaphase-promoting complex
- spindle
- cytosol
- nucleoplasm
Molecular Function
What the gene product does at the molecular level
- protein phosphatase binding