Anapc7

Predicted to enable enzyme-substrate adaptor activity and protein phosphatase binding activity. Predicted to be involved in several processes, including anaphase-promoting complex-dependent catabolic process; positive regulation of mitotic metaphase/anaphase transition; and protein polyubiquitination. Predicted to be located in heterochromatin; nucleus; and spindle. Predicted to be part of anaphase-promoting complex. Is expressed in several structures, including brain; genitourinary system; liver; lung; and spleen. Used to study syndromic intellectual disability. Orthologous to human ANAPC7 (anaphase promoting complex subunit 7). [provided by Alliance of Genome Resources, Apr 2025]

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Anapc7 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.

Biological processes and signaling networks where the Anapc7 gene in mouse plays a role, providing insight into its function and relevance in health or disease.

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.

Describes the biological processes, cellular components, and molecular functions associated with the mouse Anapc7 gene, providing context for its role in the cell.