Filip1l Gene Summary [Rat]
Predicted to be involved in protein localization to actin cytoskeleton. Predicted to act upstream of or within several processes, including hindgut development; proteasomal protein catabolic process; and protein secretion. Predicted to be active in actin cytoskeleton and centrosome. Orthologous to human FILIP1L (filamin A interacting protein 1 like). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Filip1l |
| Official Name | filamin A interacting protein 1-like [Source:RGD Symbol;Acc:1565927] |
| Ensembl ID | ENSRNOG00000001645 |
| Bio databases IDs | |
| Aliases | filamin A interacting protein 1-like |
| Synonyms | 4631422O05Rik, DOC-1, filamin A interacting protein 1-like, GIP90, LOC102724841, RGD1565927 |
| Species | Rat, Rattus norvegicus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Filip1l often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- Mitotic checkpoint protein
- Tropomyosin
- PspA/IM30 family
- Synaptonemal complex protein 1 (SCP-1)
- Cortactin-binding protein-2
- helix-rich Mycoplasma protein
- protein binding
- Calcium binding and coiled-coil domain (CALCOCO1) like
- Septation ring formation regulator, EzrA
- HOOK protein coiled-coil region
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
- uterine serous papillary cancer
- cleft lip
- gout
- autosomal dominant polycystic kidney disease
regulates
role in cell
- expression in
- growth
- ubiquitination in
- assembly in
- cytokinesis in
- assembly
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Nucleus
- centrosome
- granules
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the rat Filip1l gene, providing context for its role in the cell.
Cellular Component
Where in the cell the gene product is active
- nucleus
- cytoplasm
- membrane