FILIP1L Gene Summary [Human]
Predicted to be located in cytoplasm; membrane; and nucleus. [provided by Alliance of Genome Resources, Apr 2022]
Details
| Type | Processed Transcript |
| Official Symbol | FILIP1L |
| Official Name | filamin A interacting protein 1 like [Source:HGNC Symbol;Acc:HGNC:24589] |
| Ensembl ID | ENSG00000168386 |
| Bio databases IDs | |
| Aliases | filamin A interacting protein 1 like, downregulated in ovarian cancer 1, GPBP-interacting protein of 130 kDa |
| Synonyms | 4631422O05Rik, DOC-1, filamin A interacting protein 1-like, GIP90, LOC102724841, RGD1565927 |
| Species | Human, Homo sapiens |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human FILIP1L often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- Mitotic checkpoint protein
- Tropomyosin
- PspA/IM30 family
- Synaptonemal complex protein 1 (SCP-1)
- Cortactin-binding protein-2
- helix-rich Mycoplasma protein
- protein binding
- Calcium binding and coiled-coil domain (CALCOCO1) like
- Septation ring formation regulator, EzrA
- HOOK protein coiled-coil region
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
- uterine serous papillary cancer
- cleft lip
- gout
- autosomal dominant polycystic kidney disease
regulates
role in cell
- expression in
- growth
- ubiquitination in
- assembly in
- cytokinesis in
- assembly
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Nucleus
- centrosome
- granules
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the human FILIP1L gene, providing context for its role in the cell.
Cellular Component
Where in the cell the gene product is active
- nucleus
- cytoplasm
- membrane