Tm4sf19 Gene Summary [Rat]
Predicted to enable protein homodimerization activity. Predicted to be involved in positive regulation of osteoclast differentiation. Predicted to be located in actin cytoskeleton and filopodium. Predicted to be active in membrane. Orthologous to human TM4SF19 (transmembrane 4 L six family member 19). [provided by Alliance of Genome Resources, Apr 2025]
Details
| Type | Protein Coding |
| Official Symbol | Tm4sf19 |
| Official Name | transmembrane 4 L six family member 19 [Source:RGD Symbol;Acc:1560486] |
| Ensembl ID | ENSRNOG00000001757 |
| Bio databases IDs | |
| Aliases | transmembrane 4 L six family member 19 |
| Synonyms | EG277203, OCTM4, RGD1560486, transmembrane 4 L six family member 19 |
| Species | Rat, Rattus norvegicus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Tm4sf19 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- L6 membrane protein
- protein homodimerization
- protein binding
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
- epithelial cancer
- liver cancer
- androgenic alopecia
- colon adenocarcinoma
- colon epithelial cancer
- chronic obstructive pulmonary disease
- renal clear cell adenocarcinoma
- renal clear cell cancer
- hepatocellular carcinoma
- urothelial bladder carcinoma
role in cell
- differentiation
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Plasma Membrane
- cellular membrane
- actin cytoskeleton
- filopodia
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the rat Tm4sf19 gene, providing context for its role in the cell.
Cellular Component
Where in the cell the gene product is active
- membrane
Molecular Function
What the gene product does at the molecular level
- protein binding