Aif1l Gene Summary [Rat]
Predicted to enable actin filament binding activity and calcium ion binding activity. Predicted to be involved in actin filament bundle assembly and ruffle assembly. Part of protein-containing complex. Orthologous to human AIF1L (allograft inflammatory factor 1 like). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Aif1l |
| Official Name | allograft inflammatory factor 1-like [Source:RGD Symbol;Acc:1305081] |
| Ensembl ID | ENSRNOG00000009951 |
| Bio databases IDs | |
| Aliases | allograft inflammatory factor 1-like |
| Synonyms | 2810003C17Rik, allograft inflammatory factor 1-like, C9orf58, IBA2, RGD1305081 |
| Species | Rat, Rattus norvegicus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Aif1l often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- actin filament binding
- EFh
- protein binding
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Plasma Membrane
- focal adhesions
- actin cytoskeleton
- actin filaments
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the rat Aif1l gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- ruffle assembly
- actin filament bundle assembly
Cellular Component
Where in the cell the gene product is active
- extracellular vesicular exosome
- focal adhesion
- cytoplasm
- actin cytoskeleton
- ruffle membrane
- actin filament
Molecular Function
What the gene product does at the molecular level
- actin filament binding
- calcium ion binding