Rrbp1 Gene Summary [Rat]
Predicted to be involved in signal transduction. Predicted to be located in endoplasmic reticulum. Predicted to be active in endoplasmic reticulum membrane. Orthologous to human RRBP1 (ribosome binding protein 1). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Rrbp1 |
| Official Name | ribosome binding protein 1 [Source:RGD Symbol;Acc:1306536] |
| Ensembl ID | ENSRNOG00000005958 |
| Bio databases IDs | |
| Aliases | ribosome binding protein 1 |
| Synonyms | 1700087N07Rik, 5730465C04Rik, ES130, ES/130, hES, mKIAA1398, mRRp0, mRRp10, mRRp15a, mRRp15b, mRRp16.8, mRRp1.8, mRRp2, mRRp41, mRRp47, mRRp5.4, p180, ribosome binding protein 1, Ribosome Receptor, RRp |
| Species | Rat, Rattus norvegicus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Rrbp1 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- Mitotic checkpoint protein
- chromosome segregation protein SMC, primarily archaeal type
- exonuclease SbcC
- signaling receptor activity
- Synaptonemal complex protein 1 (SCP-1)
- helix-rich Mycoplasma protein
- protein binding
- Golgin subfamily A member 5
- Invertebrate innate immunity transcript family
- Alpha helical coiled-coil rod protein (HCR)
- Ribosome receptor lysine/proline rich region
- chromosome segregation protein SMC, common bacterial type
- RecF/RecN/SMC N terminal domain
- Tropomyosin
- Intermediate filament protein
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
- liver cancer
- epithelial cancer
- hepatitis B virus-related hepatocellular carcinoma
- intracranial aneurysm
- coronary artery disease
- breast cancer
- hepatitis C virus-related hepatocellular carcinoma
- dental disorder
regulates
- Collagen type III
- FN1
- collagen
- collagen alpha1
- Collagen type VI
- COL1A2
role in cell
- apoptosis
- bundling
- association
- acetylation
- organization
- elongation
- association in
- translation in
- biosynthesis in
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- membrane fraction
- detergent resistant lipid raft fraction
- ribosome
- Endoplasmic Reticulum
- endoplasmic reticulum membrane
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the rat Rrbp1 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- protein transport
- osteoblast differentiation
- translation
Cellular Component
Where in the cell the gene product is active
- endoplasmic reticulum membrane
- membrane
- endoplasmic reticulum
- ribosome
Molecular Function
What the gene product does at the molecular level
- protein binding
- RNA binding
- signaling receptor activity