Boc Gene Summary [Rat]
Predicted to be involved in axon guidance; cell-cell adhesion; and positive regulation of myoblast differentiation. Predicted to act upstream of or within cell projection organization and smoothened signaling pathway. Located in axonal growth cone. Orthologous to human BOC (BOC cell adhesion associated, oncogene regulated). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Boc |
| Official Name | BOC cell adhesion associated, oncogene regulated [Source:RGD Symbol;Acc:1304550] |
| Ensembl ID | ENSRNOG00000002041 |
| Bio databases IDs | |
| Aliases | BOC cell adhesion associated, oncogene regulated |
| Synonyms | 4732455C11, BOC cell adhesion associated, oncogene regulated, Boi, CDON2, mFLJ00376 |
| Species | Rat, Rattus norvegicus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Boc often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- FN3
- immunoglobulin domain
- Immunoglobulin like
- Unstructured linking region I-set and fnIII on Brother of CDO
- Purple acid Phosphatase, N-terminal domain
- Immunoglobulin I-set domain
- protein binding
- Fibronectin type 3 domain
- Immunoglobulin V-set domain
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
- chronic obstructive pulmonary disease
- non-insulin-dependent diabetes mellitus
- colorectal cancer
- dental caries
- idiopathic scoliosis
- colorectal adenoma
- colorectal adenoma formation
- colonic polyp
role in cell
- expression in
- quantity
- differentiation
- development
- organization
- guidance
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Plasma Membrane
- axon component
- cell surface
- growth cone
- perikaryon
- axons
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the rat Boc gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- nervous system development
- axon guidance
- positive regulation of myoblast differentiation
Cellular Component
Where in the cell the gene product is active
- axonal growth cone
- plasma membrane
- axon
Molecular Function
What the gene product does at the molecular level
- protein binding