Lxn Gene Summary [Rat]
Predicted to enable metalloendopeptidase inhibitor activity. Predicted to be involved in inflammatory response. Predicted to act upstream of or within detection of temperature stimulus involved in sensory perception of pain. Predicted to be located in cytoplasm. Predicted to be active in extracellular space. Orthologous to human LXN (latexin). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Lxn |
| Official Name | latexin [Source:RGD Symbol;Acc:68361] |
| Ensembl ID | ENSRNOG00000013572 |
| Bio databases IDs | |
| Aliases | latexin |
| Synonyms | ECI, latexin, TCI |
| Species | Rat, Rattus norvegicus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Lxn often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- Latexin
- protein binding
- metalloendopeptidase inhibitor
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
- obesity
- impaired glucose tolerance
- hepatic steatosis
- insulin resistance
regulates
role in cell
- differentiation
- homeostasis
- ubiquitination in
- cytostasis
- adipogenesis in
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the rat Lxn gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- inflammatory response
- detection of temperature stimulus involved in sensory perception of pain
Cellular Component
Where in the cell the gene product is active
- extracellular space
- cytoplasm
Molecular Function
What the gene product does at the molecular level
- protein binding
- heparin binding
- metalloendopeptidase inhibitor activity