Bpnt1 Gene Summary [Rat]
Enables 3'(2'),5'-bisphosphate nucleotidase activity; inositol-1,4-bisphosphate 1-phosphatase activity; and magnesium ion binding activity. Predicted to be involved in phosphatidylinositol phosphate biosynthetic process. Predicted to be located in mitochondrion. Orthologous to human BPNT1 (3'(2'), 5'-bisphosphate nucleotidase 1). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Bpnt1 |
| Official Name | 3'(2'), 5'-bisphosphate nucleotidase 1 [Source:RGD Symbol;Acc:621833] |
| Ensembl ID | ENSRNOG00000002378 |
| Bio databases IDs | |
| Aliases | 3'(2'), 5'-bisphosphate nucleotidase 1 |
| Synonyms | 3'(2'), 5'-bisphosphate nucleotidase 1, BPntase, HEL20, HsPIP, PIP, Sal3 |
| Species | Rat, Rattus norvegicus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Bpnt1 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- 3'(2'),5'-bisphosphate nucleotidase
- inositol-1,4-bisphosphate 1-phosphatase
- phosphatase
- 3'(2'),5'-bisphosphate nucleotidase, bacterial
- Inositol monophosphatase family
- FIG
- magnesium ion binding
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
- hypoproteinemia
- hypoalbuminemia
- chronic lymphocytic leukemia
- anasarca
- iron deficiency anemia
- edema
regulated by
- metribolone
- RYR1
- Ca2+
- lithium chloride
- magnesium
- dimethyl n-oxalyl-glycine
- EGLN
regulates
- cholesterol
- GPT
- ALP
- nucleic acid component or derivative
- enzyme
- 3',5'-ADP
- apolipoprotein
- phosphoadenosine phosphosulfate
role in cell
- growth
- damage
- tubulation
- abnormal morphology
- tubulation in
- fragmentation in
- aberration in
- fragmentation
- aberration
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Nucleus
- Mitochondria
- cytosol
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the rat Bpnt1 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- nervous system development
- 3'-phosphoadenosine 5'-phosphosulfate metabolic process
- phosphatidylinositol phosphorylation
- nucleobase-containing compound metabolic process
Cellular Component
Where in the cell the gene product is active
- cytosol
Molecular Function
What the gene product does at the molecular level
- 3'(2'),5'-bisphosphate nucleotidase activity
- metal ion binding
- inositol-1,4-bisphosphate 1-phosphatase activity