Cep170 Gene Summary [Rat]
Predicted to be located in centrosome; ciliary basal body; and cytosol. Predicted to be part of centriolar subdistal appendage. Predicted to be active in centriole. Orthologous to human CEP170 (centrosomal protein 170). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Cep170 |
| Official Name | centrosomal protein 170 [Source:RGD Symbol;Acc:621868] |
| Ensembl ID | ENSRNOG00000004127 |
| Bio databases IDs | |
| Aliases | centrosomal protein 170 |
| Synonyms | 4933426L22RIK, A330004A13Rik, CE170, centrosomal protein 170, FAM68A, KAB, KAB1, Karp1 Binding Protein2, KIAA0470, LOC100909664, Rhk1 |
| Species | Rat, Rattus norvegicus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Cep170 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- CEP170 C-terminus
- Inner membrane component of T3SS, cytoplasmic domain
- FHA domain
- Forkhead associated domain
- protein binding
- forkhead associated (FHA) domain superfamily
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
- Alzheimer disease
- bronchopulmonary dysplasia
- pain
- lung carcinoma
- hypertension
- lung carcinoma process
role in cell
- morphology
- organization
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Nucleus
- basal bodies
- centrosome
- centriole
- microtubules
- cytosol
- spindle fibers
- astral microtubules
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the rat Cep170 gene, providing context for its role in the cell.
Cellular Component
Where in the cell the gene product is active
- centrosome
- centriole
- spindle
- cytosol
- microtubule
Molecular Function
What the gene product does at the molecular level
- protein binding