Lrr1 Gene Summary [Rat]
Predicted to be involved in intracellular signal transduction. Orthologous to human LRR1 (leucine rich repeat protein 1). [provided by Alliance of Genome Resources, Apr 2025]
Details
| Type | Protein Coding |
| Official Symbol | Lrr1 |
| Official Name | leucine rich repeat protein 1 [Source:RGD Symbol;Acc:1589026] |
| Ensembl ID | ENSRNOG00000004216 |
| Bio databases IDs | |
| Aliases | leucine rich repeat protein 1 |
| Synonyms | 2410005L11RIK, 4-1BBLRR, leucine rich repeat protein 1, LOC687175, PPIL5 |
| Species | Rat, Rattus norvegicus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Lrr1 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- Leucine rich repeat
- enzyme
- protein binding
- Leucine Rich repeats (2 copies)
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
role in cell
- proliferation
- autophagy in
- replication in
- degradation in
- mitosis
- ubiquitination in
- CSN5i-3 sensitivity
- autophagy
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- cytosol
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the rat Lrr1 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- signal transduction
- protein ubiquitination
Cellular Component
Where in the cell the gene product is active
- nucleus
- cytosol
Molecular Function
What the gene product does at the molecular level
- protein binding