Snrpb2 Gene Summary [Rat]
Enables snRNP binding activity. Predicted to be involved in mRNA splicing, via spliceosome. Part of small nuclear ribonucleoprotein complex. Human ortholog(s) of this gene implicated in connective tissue disease. Orthologous to human SNRPB2 (small nuclear ribonucleoprotein polypeptide B2). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Snrpb2 |
| Official Name | small nuclear ribonucleoprotein polypeptide B2 [Source:RGD Symbol;Acc:1310194] |
| Ensembl ID | ENSRNOG00000004967 |
| Bio databases IDs | |
| Aliases | small nuclear ribonucleoprotein polypeptide B2 |
| Synonyms | 2810052G09Rik, Msl1, small nuclear ribonucleoprotein polypeptide B2, U2-B, U2B'', U2 small nuclear ribonucleoprotein B, U2 SNRNP B'' |
| Species | Rat, Rattus norvegicus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Snrpb2 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- RNA recognition motif (RRM) superfamily
- RNA recognition motif
- ribonucleoprotein binding
- protein binding
Pathways
Biological processes and signaling networks where the Snrpb2 gene in rat plays a role, providing insight into its function and relevance in health or disease.
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Nucleus
- fibrillar center
- catalytic step 2 spliceosome
- cytoplasmic ribonucleoprotein granule
- intranuclear region
- spliceosomes
- nucleoplasm
- nuclear speckles
- coiled body
- perikaryon
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the rat Snrpb2 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- nuclear mRNA splicing, via spliceosome
Cellular Component
Where in the cell the gene product is active
- nucleus
- catalytic step 2 spliceosome
- nuclear speck
- U2-type catalytic step 2 spliceosome
- spliceosomal complex
- U2-type spliceosomal complex
- U2-type precatalytic spliceosome
- U2 snRNP
- U1 snRNP
- fibrillar center
- nucleoplasm
Molecular Function
What the gene product does at the molecular level
- protein binding
- U1 snRNA binding