Rps23 Gene Summary [Rat]

Predicted to be a structural constituent of ribosome. Predicted to be involved in ribosomal small subunit biogenesis; stress granule assembly; and translation. Part of cytosolic small ribosomal subunit. Human ortholog(s) of this gene implicated in brachycephaly, trichomegaly, and developmental delay. Orthologous to human RPS23 (ribosomal protein S23). [provided by Alliance of Genome Resources, Jul 2025]

Details

Type
Protein Coding
Official Symbol
Rps23
Official Name
ribosomal protein S23 [Source:RGD Symbol;Acc:621039]
Ensembl ID
ENSRNOG00000016580
Bio databases IDs NCBI: 124323 Ensembl: ENSRNOG00000016580
Aliases ribosomal protein S23
Synonyms 2410044J15Rik, BTDD, MABAS, MCINS, PAMAS, ribosomal protein S23, Riken clone:2410029n08, S23, uS12
Species
Rat, Rattus norvegicus
OrthologiesHumanMouse

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Rps23 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • structural constituent of ribosome
  • protein binding
  • Ribosomal_S12_like
  • translation regulator

Pathways

Biological processes and signaling networks where the Rps23 gene in rat plays a role, providing insight into its function and relevance in health or disease.

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
  • MacInnes syndrome
  • flu
  • endometriosis
regulated by
  • LH
  • MYCN
  • dexamethasone
  • sirolimus
  • EPO
  • 5-fluorouracil
  • KITLG
  • SPEN
  • Influenza A virus (A/Japan/305/57(H2N2))
  • MYC
regulates
  • RNR
role in cell
  • processing in
  • translation in
  • assembly

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Cytoplasm
  • pre-ribosome
  • ribosome
  • Endoplasmic Reticulum
  • cytosol
  • nucleoplasm
  • synapse

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the rat Rps23 gene, providing context for its role in the cell.

Biological Process

Functions and activities the gene product is involved in
  • stress granule assembly
  • cytoplasmic translation
  • ribosomal small subunit biogenesis
  • translation

Cellular Component

Where in the cell the gene product is active
  • small-subunit processome
  • cytosolic ribosome
  • cytosolic small ribosomal subunit
  • rough endoplasmic reticulum
  • endoplasmic reticulum
  • synapse
  • nucleolus
  • ribosome
  • nucleoplasm
  • cytoplasm
  • membrane
  • cytosol

Molecular Function

What the gene product does at the molecular level
  • RNA binding
  • protein binding
  • structural constituent of ribosome

Gene-Specific Assays for Results You Can Trust

Streamline your workflow with assays designed for this gene. Our targeted dPCR and qPCR assays help you generate meaningful data – efficiently and accurately.