Rnf103 Gene Summary [Rat]
Predicted to enable ubiquitin-protein transferase activity. Predicted to be involved in ERAD pathway and protein ubiquitination. Predicted to be located in endoplasmic reticulum membrane. Predicted to be active in endoplasmic reticulum. Used to study depressive disorder. Orthologous to human RNF103 (ring finger protein 103). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Rnf103 |
| Official Name | ring finger protein 103 [Source:RGD Symbol;Acc:620586] |
| Ensembl ID | ENSRNOG00000007272 |
| Bio databases IDs | |
| Aliases | ring finger protein 103 |
| Synonyms | Adrg34, HKF-1, KF-1, ring finger protein 103, ZFP-103 |
| Species | Rat, Rattus norvegicus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Rnf103 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- ubiquitin protein ligase activity
- zinc finger of C3HC4-type, RING
- enzyme
- Ring finger domain
- protein binding
- RING-like zinc finger
- RING-type zinc-finger
- RING finger (Really Interesting New Gene) domain and U-box domain superfamily
- Ring finger
- ubiquitin-protein transferase activity
- tail domain
- Zinc finger, C3HC4 type (RING finger)
- zinc-RING finger domain
- Anaphase-promoting complex subunit 11 RING-H2 finger
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- cellular membrane
- Endoplasmic Reticulum
- endoplasmic reticulum membrane
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the rat Rnf103 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- central nervous system development
- protein ubiquitination
Cellular Component
Where in the cell the gene product is active
- endoplasmic reticulum membrane
- endoplasmic reticulum
Molecular Function
What the gene product does at the molecular level
- ubiquitin-protein ligase activity
- protein binding
- metal ion binding