Rps20 Gene Summary [Rat]
Predicted to enable MDM2/MDM4 family protein binding activity and ubiquitin ligase inhibitor activity. Predicted to be a structural constituent of ribosome. Predicted to be involved in positive regulation of signal transduction by p53 class mediator. Part of cytosolic small ribosomal subunit. Orthologous to human RPS20 (ribosomal protein S20). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Rps20 |
| Official Name | ribosomal protein S20 [Source:RGD Symbol;Acc:621037] |
| Ensembl ID | ENSRNOG00000008555 |
| Bio databases IDs | |
| Aliases | ribosomal protein S20 |
| Synonyms | 4632426K06Rik, Dsk4, ribosomal protein S20, S20, uS10 |
| Species | Rat, Rattus norvegicus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Rps20 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- structural constituent of ribosome
- enzyme inhibitor activity
- Ribosomal protein S10p/S20e
- protein binding
- enzyme regulator activity
- rpsJ
Pathways
Biological processes and signaling networks where the Rps20 gene in rat plays a role, providing insight into its function and relevance in health or disease.
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
- Diamond-Blackfan anemia
- Lynch syndrome
- systemic lupus erythematosus
- diabetes mellitus
- myelodysplastic syndrome
- flu
role in cell
- expression in
- cell death
- translation in
- stabilization in
- ubiquitination in
- autoubiquitination in
- nuclear export in
- processing in
- G2 phase
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- ribosome
- cytosol
- nucleoplasm
- synapse
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the rat Rps20 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- cytoplasmic translation
- translation
Cellular Component
Where in the cell the gene product is active
- extracellular vesicular exosome
- cytosolic ribosome
- cytosolic small ribosomal subunit
- cytoplasm
- membrane
- cytosol
- synapse
- nucleoplasm
Molecular Function
What the gene product does at the molecular level
- RNA binding
- protein binding
- structural constituent of ribosome