Pcdh18 Gene Summary [Rat]

Predicted to enable calcium ion binding activity. Predicted to be involved in brain development and cell adhesion. Predicted to be active in plasma membrane. Orthologous to human PCDH18 (protocadherin 18). [provided by Alliance of Genome Resources, Apr 2025]

Details

Type
Protein Coding
Official Symbol
Pcdh18
Official Name
protocadherin 18 [Source:RGD Symbol;Acc:1305870]
Ensembl ID
ENSRNOG00000009949
Bio databases IDs NCBI: 295027 Ensembl: ENSRNOG00000009949
Aliases protocadherin 18
Synonyms 3110038E07Rik, PCDH68L, protocadherin 18
Species
Rat, Rattus norvegicus
OrthologiesHumanMouse

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Pcdh18 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • Cadherin-like
  • Cadherin repeat-like domain
  • protein binding

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
binds
regulated by
regulates
  • cytokine
role in cell
  • cell viability
  • replication in

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Extracellular Space
  • cellular membrane

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the rat Pcdh18 gene, providing context for its role in the cell.

Biological Process

Functions and activities the gene product is involved in
  • cell adhesion
  • brain development
  • homophilic cell adhesion

Cellular Component

Where in the cell the gene product is active
  • plasma membrane

Molecular Function

What the gene product does at the molecular level
  • protein binding
  • calcium ion binding

Gene-Specific Assays for Results You Can Trust

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