Pcdh18 Gene Summary [Mouse]
Predicted to enable calcium ion binding activity. Involved in brain development. Predicted to be active in plasma membrane. Is expressed in several structures, including adipose tissue; brain; genitourinary system; gut; and hemolymphoid system gland. Orthologous to human PCDH18 (protocadherin 18). [provided by Alliance of Genome Resources, Apr 2025]
Details
| Type | Protein Coding |
| Official Symbol | Pcdh18 |
| Official Name | protocadherin 18 [Source:MGI Symbol;Acc:MGI:1920423] |
| Ensembl ID | ENSMUSG00000037892 |
| Bio databases IDs | |
| Aliases | protocadherin 18 |
| Synonyms | 3110038E07Rik, PCDH68L, protocadherin 18 |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Pcdh18 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- Cadherin-like
- Cadherin repeat-like domain
- protein binding
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Extracellular Space
- cellular membrane
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Pcdh18 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- cell adhesion
- brain development
- homophilic cell adhesion
Cellular Component
Where in the cell the gene product is active
- plasma membrane
Molecular Function
What the gene product does at the molecular level
- protein binding
- calcium ion binding