LOC103694863 Gene Summary [Rat]

Predicted to enable GTP binding activity and GTPase activity. Predicted to be involved in positive regulation of peptide hormone secretion and regulation of systemic arterial blood pressure by atrial natriuretic peptide. Orthologous to human RASL10B (RAS like family 10 member B). [provided by Alliance of Genome Resources, Apr 2025]

Details

Type
Protein Coding
Official Symbol
LOC103694863
Official Name
ras-like protein family member 10B [Source:RGD Symbol;Acc:9359312]
Ensembl ID
ENSRNOG00000010302
Bio databases IDs NCBI: 303382 Ensembl: ENSRNOG00000010302
Aliases ras-like protein family member 10B
Synonyms B230331P10, B230331P10Rik, Gm729, LOC100912246, LOC103694863, RAS like family 10 member B, RAS-like, family 10, member B, RRP17, VTS58635
Species
Rat, Rattus norvegicus
OrthologiesHumanMouse

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Loc103694863 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • small GTP-binding protein domain
  • Small GTPase of the Ras superfamily (ill-defined subfamily)
  • Ras family
  • 50S ribosome-binding GTPase
  • Rab subfamily of small GTPases
  • enzyme
  • protein binding
  • Ras of Complex, Roc, domain of DAPkinase
  • Rho (Ras homology) subfamily of Ras-like small GTPases
  • P-loop containing Nucleoside Triphosphate Hydrolases
  • Ras subfamily of RAS small GTPases

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
  • hypertension
  • diabetic nephropathy
regulated by
regulates
role in cell
  • size
  • abnormal morphology

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • insoluble fractions
  • perinuclear region

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the rat Loc103694863 gene, providing context for its role in the cell.

Biological Process

Functions and activities the gene product is involved in
  • regulation of systemic arterial blood pressure by atrial natriuretic peptide
  • positive regulation of peptide hormone secretion

Cellular Component

Where in the cell the gene product is active
  • plasma membrane

Molecular Function

What the gene product does at the molecular level
  • GTP binding
  • protein binding
  • small monomeric GTPase activity

Gene-Specific Assays for Results You Can Trust

Streamline your workflow with assays designed for this gene. Our targeted dPCR and qPCR assays help you generate meaningful data – efficiently and accurately.