Rasl10b Gene Summary [Mouse]
Predicted to enable G protein activity and GTP binding activity. Involved in positive regulation of peptide hormone secretion and regulation of systemic arterial blood pressure by atrial natriuretic peptide. Predicted to be located in plasma membrane. Is expressed in several structures, including brain; heart; myotome; neural tube; and retina. Orthologous to human RASL10B (RAS like family 10 member B). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Rasl10b |
| Official Name | RAS-like, family 10, member B [Source:MGI Symbol;Acc:MGI:2685575] |
| Ensembl ID | ENSMUSG00000020684 |
| Bio databases IDs | |
| Aliases | RAS-like, family 10, member B |
| Synonyms | B230331P10, B230331P10Rik, Gm729, LOC100912246, LOC103694863, RAS like family 10 member B, RAS-like, family 10, member B, RRP17, VTS58635 |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Rasl10b often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- small GTP-binding protein domain
- Small GTPase of the Ras superfamily (ill-defined subfamily)
- Ras family
- 50S ribosome-binding GTPase
- Rab subfamily of small GTPases
- enzyme
- protein binding
- Ras of Complex, Roc, domain of DAPkinase
- Rho (Ras homology) subfamily of Ras-like small GTPases
- P-loop containing Nucleoside Triphosphate Hydrolases
- Ras subfamily of RAS small GTPases
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- insoluble fractions
- perinuclear region
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Rasl10b gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- regulation of systemic arterial blood pressure by atrial natriuretic peptide
- positive regulation of peptide hormone secretion
Cellular Component
Where in the cell the gene product is active
- plasma membrane
Molecular Function
What the gene product does at the molecular level
- GTP binding
- protein binding
- small monomeric GTPase activity