Matn1 Gene Summary [Rat]
Predicted to enable calcium ion binding activity. Predicted to act upstream of or within growth plate cartilage chondrocyte morphogenesis and regulation of bone mineralization. Predicted to be located in extracellular matrix. Predicted to be active in collagen-containing extracellular matrix. Orthologous to human MATN1 (matrilin 1). [provided by Alliance of Genome Resources, Apr 2025]
Details
| Type | Protein Coding |
| Official Symbol | Matn1 |
| Official Name | matrilin 1 [Source:RGD Symbol;Acc:1359410] |
| Ensembl ID | ENSRNOG00000010932 |
| Bio databases IDs | |
| Aliases | matrilin 1 |
| Synonyms | CMP, CRTM, Mat1, Matrilin-1, matrilin 1, cartilage matrix protein |
| Species | Rat, Rattus norvegicus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Matn1 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- von Willebrand factor (vWF) type A domain
- Trimeric coiled-coil oligomerization domain of matrilin
- vWFA
- extracellular matrix structural constituent
- coiled-coil domain
- von Willebrand factor type A domain
- protein binding
- Coagulation Factor Xa inhibitory site
- EGF_CA
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Extracellular Space
- cell-associated matrix
- extracellular matrix
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the rat Matn1 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- macromolecular complex assembly
- growth plate cartilage chondrocyte morphogenesis
- extracellular matrix organization
- regulation of bone mineralization
Cellular Component
Where in the cell the gene product is active
- extracellular matrix
- extracellular region
Molecular Function
What the gene product does at the molecular level
- protein binding
- calcium ion binding
- extracellular matrix structural constituent