Dctd Gene Summary [Rat]

Predicted to enable 5-hydroxymethyl-dUMP N-hydrolase activity; dCMP deaminase activity; and identical protein binding activity. Predicted to be involved in nucleobase-containing small molecule metabolic process. Predicted to be active in cytoplasm. Orthologous to human DCTD (dCMP deaminase). [provided by Alliance of Genome Resources, Apr 2025]

Details

Type
Protein Coding
Official Symbol
Dctd
Official Name
dCMP deaminase [Source:RGD Symbol;Acc:1359671]
Ensembl ID
ENSRNOG00000013215
Bio databases IDs NCBI: 290741 Ensembl: ENSRNOG00000013215
Aliases dCMP deaminase
Synonyms 6030466N05Rik, dCMP deaminase
Species
Rat, Rattus norvegicus
OrthologiesHumanMouse

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Dctd often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • cytidine_deaminase-like
  • MafB19-like deaminase
  • Cytidine and deoxycytidylate deaminase zinc-binding region
  • N-glycosyl glycosylase
  • enzyme
  • protein binding
  • identical protein binding
  • dCMP deaminase

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
  • androgenic alopecia
regulated by
regulates
  • dCMP
  • Ara-CTP
  • dTTP
  • pyrimidine 5'-nucleotide
role in cell
  • cell death

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Cytoplasm
  • cytosol

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the rat Dctd gene, providing context for its role in the cell.

Biological Process

Functions and activities the gene product is involved in
  • nucleoside salvage
  • nucleotide biosynthetic process
  • cytidine deamination
  • pyrimidine nucleotide metabolic process

Cellular Component

Where in the cell the gene product is active
  • cytoplasm
  • cytosol

Molecular Function

What the gene product does at the molecular level
  • identical protein binding
  • zinc ion binding
  • protein binding
  • deoxyribonucleoside 5'-monophosphate N-glycosidase activity
  • dCMP deaminase activity

Gene-Specific Assays for Results You Can Trust

Streamline your workflow with assays designed for this gene. Our targeted dPCR and qPCR assays help you generate meaningful data – efficiently and accurately.