Dctd Gene Summary [Mouse]
Predicted to enable 5-hydroxymethyl-dUMP N-hydrolase activity; dCMP deaminase activity; and identical protein binding activity. Predicted to be involved in nucleobase-containing small molecule metabolic process. Predicted to be active in cytoplasm. Is expressed in several structures, including alimentary system; cranium; integumental system; nervous system; and respiratory system. Orthologous to human DCTD (dCMP deaminase). [provided by Alliance of Genome Resources, Apr 2025]
Details
| Type | Protein Coding |
| Official Symbol | Dctd |
| Official Name | dCMP deaminase [Source:MGI Symbol;Acc:MGI:2444529] |
| Ensembl ID | ENSMUSG00000031562 |
| Bio databases IDs | |
| Aliases | dCMP deaminase |
| Synonyms | 6030466N05Rik, dCMP deaminase |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Dctd often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- cytidine_deaminase-like
- MafB19-like deaminase
- Cytidine and deoxycytidylate deaminase zinc-binding region
- N-glycosyl glycosylase
- enzyme
- protein binding
- identical protein binding
- dCMP deaminase
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- cytosol
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Dctd gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- nucleoside salvage
- nucleotide biosynthetic process
- cytidine deamination
- pyrimidine nucleotide metabolic process
Cellular Component
Where in the cell the gene product is active
- cytoplasm
- cytosol
Molecular Function
What the gene product does at the molecular level
- identical protein binding
- zinc ion binding
- protein binding
- deoxyribonucleoside 5'-monophosphate N-glycosidase activity
- dCMP deaminase activity