Stard7 Gene Summary [Rat]
Predicted to enable molecular carrier activity. Predicted to act upstream of or within several processes, including establishment of skin barrier; mucociliary clearance; and myeloid dendritic cell activation. Predicted to be located in mitochondrion. Human ortholog(s) of this gene implicated in familial adult myoclonic epilepsy 2. Orthologous to human STARD7 (StAR related lipid transfer domain containing 7). [provided by Alliance of Genome Resources, Apr 2025]
Details
| Type | Protein Coding |
| Official Symbol | Stard7 |
| Official Name | StAR-related lipid transfer domain containing 7 [Source:RGD Symbol;Acc:1307613] |
| Ensembl ID | ENSRNOG00000013479 |
| Bio databases IDs | |
| Aliases | StAR-related lipid transfer domain containing 7 |
| Synonyms | ADCME, BAFME2, FAME, FAME2, FCMTE2, GTT1, StAR-related lipid transfer domain containing 7 |
| Species | Rat, Rattus norvegicus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Stard7 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- SRPBCC domain
- lipid transporter
- protein binding
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
- atopic dermatitis
- airway hyperresponsiveness
- lung adenocarcinoma formation
- adult familial myoclonic epilepsy type 2
- lung adenocarcinoma
- pneumonitis
- metaplasia
- chronic periodontal disease
role in cell
- quantity
- activation
- lipotoxicity in
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- Mitochondria
- cytosol
- mitochondrial outer membrane
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the rat Stard7 gene, providing context for its role in the cell.
Cellular Component
Where in the cell the gene product is active
- mitochondrial outer membrane
Molecular Function
What the gene product does at the molecular level
- protein binding
- lipid binding