Sh3bgrl3 Gene Summary [Rat]

Located in nuclear body. [provided by Alliance of Genome Resources, Apr 2022]

Details

Type
Protein Coding
Official Symbol
Sh3bgrl3
Official Name
SH3 domain binding glutamate-rich protein like 3 [Source:RGD Symbol;Acc:1308118]
Ensembl ID
ENSRNOG00000015967
Bio databases IDs NCBI: 298544 Ensembl: ENSRNOG00000015967
Aliases SH3 domain binding glutamate-rich protein like 3
Synonyms 1110004L05Rik, HEL-S-297, SH3BP-1, SH3 domain binding glutamate-rich protein like 3, SH3 domain binding glutamic acid-rich protein-like 3, TIP-B1
Species
Rat, Rattus norvegicus
OrthologiesHumanMouse

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Sh3bgrl3 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • Protein Disulfide Oxidoreductases and Other Proteins with a Thioredoxin fold
  • protein binding

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
  • chronic sinusitis
  • diabetes mellitus
regulated by
  • levodopa
  • SOD1
  • PNPLA2
  • 10:0/10:0/10:0 triacylglycerol
  • HMOX2
  • MIRN1
  • CSN5i-3
  • mir-122 (includes others)
  • CD 437
role in cell
  • apoptosis
  • cytolysis
  • organization

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Nucleus
  • Cytoplasm
  • cytosol
  • membrane ruffles
  • nuclear bodies

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the rat Sh3bgrl3 gene, providing context for its role in the cell.

Biological Process

Functions and activities the gene product is involved in
  • cytoskeleton organization

Cellular Component

Where in the cell the gene product is active
  • nuclear body
  • extracellular vesicular exosome
  • cytoplasm
  • ruffle membrane
  • cytosol

Molecular Function

What the gene product does at the molecular level
  • protein binding
  • glutathione transferase activity

Gene-Specific Assays for Results You Can Trust

Streamline your workflow with assays designed for this gene. Our targeted dPCR and qPCR assays help you generate meaningful data – efficiently and accurately.