Rpl7l1 Gene Summary [Rat]

Predicted to enable RNA binding activity. Predicted to be a structural constituent of ribosome. Predicted to be involved in maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA). Predicted to act upstream of or within blastocyst formation. Predicted to be located in mitochondrion and nucleolus. Predicted to be part of cytosolic large ribosomal subunit. Orthologous to human RPL7L1 (ribosomal protein L7 like 1). [provided by Alliance of Genome Resources, Jul 2025]

Details

Type
Protein Coding
Official Symbol
Rpl7l1
Official Name
ribosomal protein L7-like 1 [Source:RGD Symbol;Acc:1308469]
Ensembl ID
ENSRNOG00000016269
Bio databases IDs NCBI: 317275 Ensembl: ENSRNOG00000016269
Aliases ribosomal protein L7-like 1
Synonyms 1500016H10Rik, dJ475N16.4, RGD1308469, ribosomal protein L7-like 1
Species
Rat, Rattus norvegicus
OrthologiesHumanMouse

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Rpl7l1 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • 60S ribosomal protein uL30, eukaryotic form
  • Ribosomal protein L30p/L7e
  • transcription regulator
  • Ribosomal_L30_like
  • protein binding
  • Ribosomal L30 N-terminal domain

Pathways

Biological processes and signaling networks where the Rpl7l1 gene in rat plays a role, providing insight into its function and relevance in health or disease.

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
  • coronary artery disease
  • myelodysplastic syndrome
regulated by

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Cytoplasm
  • Mitochondria
  • cytosol
  • nucleoli

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the rat Rpl7l1 gene, providing context for its role in the cell.

Biological Process

Functions and activities the gene product is involved in
  • maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
  • blastocyst formation

Cellular Component

Where in the cell the gene product is active
  • cytosolic large ribosomal subunit
  • nucleolus

Molecular Function

What the gene product does at the molecular level
  • RNA binding
  • protein binding
  • structural constituent of ribosome

Gene-Specific Assays for Results You Can Trust

Streamline your workflow with assays designed for this gene. Our targeted dPCR and qPCR assays help you generate meaningful data – efficiently and accurately.