Snx7 Gene Summary [Rat]
This gene encodes a member of the sorting nexin family. Members of this family contain a phox (PX) domain, which is a phosphoinositide binding domain, and are involved in intracellular trafficking. This protein does not contain a coiled coil region like some family members, and its exact function is unknown. Alternative splicing results in multiple transcript variants. A related pseudogene has been identified on chromosome 11. [provided by RefSeq, Jun 2010]
Details
| Type | Protein Coding |
| Official Symbol | Snx7 |
| Official Name | sorting nexin 7 [Source:RGD Symbol;Acc:1305480] |
| Ensembl ID | ENSRNOG00000017077 |
| Bio databases IDs | |
| Aliases | sorting nexin 7 |
| Synonyms | 2510028H01Rik, DKFZp564F052, LOC100910063, LOC108348210, sorting nexin 7 |
| Species | Rat, Rattus norvegicus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Snx7 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- The Phox Homology domain, a phosphoinositide binding module
- protein binding
- Bin/Amphiphysin/Rvs domain
- PX domain
- transporter
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- early endosomes
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the rat Snx7 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- piecemeal microautophagy of nucleus
- protein transport
- positive regulation of autophagic vacuole assembly
- mitochondrion degradation
- endocytic recycling
Cellular Component
Where in the cell the gene product is active
- early endosome membrane
- early endosome
- pre-autophagosomal structure
Molecular Function
What the gene product does at the molecular level
- protein binding
- phosphatidylinositol binding